PT Confirmation

Has anyone with fertility assistance had trouble discovering they where pregnant until too late or was not aware of symptoms until after the time for the missed period? I ask, as it seems your significant other would know, and if you have a midwife would they continue to make you take medication until you are pregnant (if not)?

To explain; I am researching or interested in how it works for anyone who hires a midwife (just in case) you become pregnant. So before, during, and after of course. To be safe!