Is IVF worth a try for unexplained?

Question

My husband and I have been TTC for almost 3 years now with not one BFP. We have been through all the testing and everything looks perfect. We did 4 medicated IUI's with no luck. 
The issue is we live in a province in Canada that offers zero coverage for IVF so we could only give it one try and even that will be very challenging financially. So for anyone with experience do you think it's worth a shot if you know if it fails there is no option for a second try?

Answer

I definitely think so. It’s unexplained, like you’re both healthy just not conceiving for some reason? You ovulate? Hormone levels are all normal? Uterus and ovaries look good? Husband/partners sperm is normal? If so, I would try it. 
I’m in the US and MOST insurance companies here do not cover IVF. They may cover some of the testing done and ultrasounds or other things but not the entirety of it. Fertility clinics here typically offer some sort of financing. 
Assuming you are able to get several embryos from your egg retrial, you could freeze the others. If the first transfer doesn’t take, it if far less expensive to do a FET than to do an entire cycle again. 
We did IVF/FET bc my husband had a vasectomy in his early 20s and 7-8yrs later when we met, were married, and decided we wanted more children, he had the reversal, his swimmers were not as active. Low motility or mobility. I don’t remember which one. They were locked up for almost too long. I was completely heathy. We still were able to use his fresh sperm bc they can put the sperm and egg together in the dish to create the embryo. So they didn’t have to do much work themselves. Our 1st transfer worked and I’m currently in my 28th week of pregnancy. 
I would think that as long as they aren’t finding anything wrong with you but for some reason your all’s sperm and egg just aren’t connecting on their own that you have a great chance of it working the 1st time. I know of several other women that had IVF that worked the 1st time as well. Being the woman and the “host” Ik that’s not the greatest wording but that’s what it is, I think the possibility of success is way higher when you are healthy and “not the problem”. Ik again that’s terrible wording but the truth. I think you could have pretty good odds of success. Yes, it’s expensive but so are kids in general. It’s also worth it, imo.

Answer

@MW I am also unexplained and 3 failed IUIs. I start now looking into IVF as well.  This post of yours was great to see to the other unexplained infertility cases that could be solved with IVF. Do you already have a plan to when you start? Let us keep in touch 😊

Answer

I am in England, but we recently had IVF following technically ‘unexplained infertility’ (they did find one poly cystic ovary) and we got pregnant on our first try of IVF. Even after I did not respond very well to the drugs.
However we weren’t offered any kind of IUI first. I think this might be the difference in countries though... US/Canada seem to try IUIs first whereas UK (nhs) would go straight for IVF - or they seem to in my county. Or that’s how it seems after a couple of years on this app!!!
I’ve got to say we only have one free try in our area then we have to pay too. The odds that they quote here (NICE guidelines) are that it takes 1 in 3 tries to successfully get pregnant by IVF. But all our doctors pointed out that this is over a broad spectrum so it includes people with specific issues, those over 40 etc. 
We were willing and ready to pay for our 2nd or 3rd rounds, if we had had to. And we made sure we were ready before we started round 1s

Answer

I’m in Ontario. Even though funding is available it’s actually not. The waitlist is 2-3 years. And I feel like they are essentially playing banker with peoples fertility, which is awful. 
I’ve been on the list since last April (1 year). I got an email before everything closed for COVID saying that I wasn’t being given funding for the new cycle year (it’s April to April). So we decided to just pay out of pocket.  
We’ve come to accept it and will do whatever it takes. It’s a big decision, yes. Outweigh the pros and cons and then make a decision.  
Good luck!

Answer

I think its worth a try. I don’t want to have any regrets later on when its to late to do ivf. We have unexplained, I just turned 40, we did 3 iui’s (2failed, 1chemical) so now we are on our ivf journey.

Answer

Absolutely! I have a IVF nephew that was a result on unexplained infertility and he is perfect. He's about to be 3 in a few weeks. Don't give up on your miracle baby! I'm in the same place. We have been trying for over two years with nothing but a chemical pregnancy. We are looking into IVF as well.

Answer

I live in Germany. We try also IVF. Almost is worked perfect. But not every time. First time did not worked. Second time I was pregnant 7 weeks or less, in April last year I get diagnosis "Missed Abortion". 😭 We try again in August. And I was thinking positive (she is fine, this time I will have my baby girl). But in November I was visiting doctor for prenatal medicine and he told us that she don't have corpus callosum but she can live without that. I was live in hoping. In January everything looks fine just this part from November missing. In February I was visiting again doctor for prenatal medicine and this time my baby had problem swollen kidneys. Same again in March and same day we get phone call from ours doctor for genetic and next day we get appointment and we talk with him. Unfortunately he get me bed news. One my Gene is damage. And one in ten cells is mutated. Cases like mine are very rare. And that one mutated cell is to lead to an embryo mutation. That why my baby had not corpus callosum and problem with swollen kidneys. Also ours doctor for genetic told us she probably had short live. He could not told us how long (couple weeks, months or years). Next week we get also second opinion. At was almost the same. Or worse. She had total mental retardation. Unfortunately I asked for an pregnant termination. 😭😭😭 We will try again in couple of months with IVF. I hope so we will get healthy baby. 😭😭😭

Answer

We are unexplained.  Have never had a natural pregnancy, been dealing with Infertility for 14 years.  Have three IVF kids and about to transfer another embryo this coming week.  So yes even if your ovaries look good,  uterus is in perfect shape,  sperm is good like it has been for us,  IVF makes all the difference.

Answer

It’s totally worth it ! Did it last year February and had a baby in November. Currently 3 months pregnant with baby 2 naturally so it reset my fertility

Answer

Have you tried any inflammation/immune protocols along with the iuis? It seems to me like implantation may be the issue and those meds can help that. Also how is your uterine lining thickness?

Is IVF worth a try for unexplained?

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