It depends on what risk you're willing to accept and how having the information would change your plan. For me personally, I would want the amnio because I would consider termination in the presence of certain diagnoses. Other women would want it so they can emotionally, mentally, and financially prepare for a special needs child. Other women feel like they wouldn't terminate no matter what so having a confirmed diagnosis wouldn't change anything and they choose not to have the amnio. Ask your doctor what the risks and benefits are for having the amnio. Ask yourself and your partner (if they're involved) if whatever risk associated with the test is worth it, and whether having a diagnosis or not would change the outcome. With all this being said, there is the very rare possibility that the amnio comes back confirmatory for DS and it's incorrect. Get all the information about the amnio, explore yourself and your heart, and make the best decision for you.

I had mine come back at 1/98 chance. I had the NIPT test which came back low risk. I’ve just had a early anatomy scan at 16w and everything looked good structurally etc with baby so I will have another anatomy scan at 20w. I have been offered an amnio which would give me more certainty but with a 1/500 chance of miscarriage I’d rather wait for my 20 week scan to see the progress and what they think then before rushing a test that could effect my pregnancy

Unfortunately while baby is still inside that’s the only way to tell they check for markers (blood test gives you a high/low risk) and then further testing can show flags but unless they do the needle in the belly they can’t give a for sure answer but if their bone structure looked okay then it’s not likely they have DS, as babies with ds don’t have the same facial bones as other babies.

Yes the amniocentesis