Very naughty 5 year old!!

Please help any advice form anyone welcome, I'm really struggling with my sons behaviour he just doesn't listen I have tried everything from praising him for his good and ignoring the bad I'm trying to juggle roles of mum and dad as I'm a single mum I haven't a clue what else to do he constantly Bullies his 2 year old brother and makes him cry and is just so nasty to him, for example my two year old has a huge bite mark on his back caused by him I asked him why he did it but he says he doesn't know. I had a few issues with his behaviour at school when he first started but now is thankfully very good, it's just at home.