12 months and nothing

12 months of regular cycles, positive opks, good looking temps, great timing for sex and nothing. AF hasn't been late, no faint lines, just nothing. Tried mucinex, preseed, vitamins, sperm meets egg, every day, every other day, boxers. Calling the doctor on Monday and hopefully we can get some help and some answers. I'm so sad. My husband is sympathetic but doesn't truly feel the pain like I do. Cried all night on Thursday after the first negative test and now I just feel numb.