. I was then prescribed a weeks worth of fluconozole . I started to take it on Wednesday and it is now Sunday night and I'm not seeing a difference at all . He said I should see a difference within 3 days . My tongue is starting to burn a bit and It doesn't look worse but also doesn't look better from what I can see . How long did it take for your oral thrush to go away , what were you prescribed and how long until you saw a difference ?