PCOS and medication

Julia
Hey ladies! Ever since I hit puberty, I've had an irregular period. I was diagnosed with PCOS when I was 14, and the doctors prescribed me a number of medications to help with the period and all of the other side effects of PCOS. In the end, I was taking Estrogen for regulating my period, Metformin for the prediabetes that, along with my lifestyle, PCOS was magnifying, a depression medication, and a sleeping medication that also doubled as an anxiety medication. Plus probiotics from the yeast infections it caused, and vitamins and such, I was taking a ton of pills every day as a teenager. At age 16 I decided to stop taking everything all at once, and it actually was fine. I honestly emotionally felt way better (but that was also because other situations had gotten better for me), and physically I felt okay as well.
Flash forward two years and I'm an entirely new person. And while stopping all the medication seemed to work for my mental health (btw I'm totally not advocating that for anyone else, it just was best for me at the time), my periods are only maybe like three times a year, and I am clinically obese (6'00" at 290). For my ladies out there with PCOS and other health issues, how has medication affected your daily lives and your physical health. Is there any advice you have?