Should I say something?

One of my best friends throughout high school has spent the last year at university, quite a few hours away from me. We often catch up online and are still good friends. I'm becoming concerned for her because of what she's doing with guys at her uni. She has only been having sex for about a year and a half and I think she's gone sex mad. She finds so many different guys that I can't keep track of them anymore. I'd estimate from what she's told me that she's had sex with about 50 guys this year. I know it's not my business but she often forms emotional attachments to these guys and frequently gets heartbroken over it. I don't think she has the right mindset to have so many partners and remain emotionless. She's lonely but going about it the wrong way I think, and I'm worried she'll come out of it feeling like she's been around a bit much or makes a mistake and comes away with something permanent (I know that at least once before she's merely trusted that a guy won't have an STD and didn't use protection). I don't think any of her other friends see the potential ramifications of what she's doing. Should I say something?