So this is my second d week taking methotrexate for A.S. Which I can see that it's helping. Advised not to get pregnant while taking the shot because it can also be taken to end chemical or other problem pregnancies. Hoping in 4-6 months ill be off and can try for a baby. My health has been really bad but this is really helping and it makes me feel hopeful that one day soon I'll have our rainbow baby. Anyone experienced taking methotrexate and successful conceived afterwards??? It would really be encouraging to know there great ending to this