Small children holding newborn

I have 7 nieces and nephews between age 2-9, and when I have my baby in two months I know everyone is coming to visit. Im not sure if I’m comfortable having small children hold my brand new baby between hand washing, one family always has some kind of cold going on....Knowing my family, their parents will say it’s fine we will just have them sit and hold the baby, make a big deal, now I’ve disappointed little Jamie because I said no after her mom said yes. Sigh 😔

Any advice?