Therapy and medicine doesn’t work

I need some help. For the past 10 years I’ve struggled with severe anxiety (to the point that I can’t have a job) depression and suicidal thoughts as well as self harm. I’ve been in therapy from the beginning and been on multiple medications. I’m married, have 3 kids and have a good life. But these don’t go away. Therapy does absolutely nothing, I’ve been to many different people.

I’ve done so many things to move on. I’ve taken weekends to myself, yoga, music, meditation, etc.

It’s just like nothing works. There’s no “deeper problem” I’ve always been like this since I was little. I had everything, and never felt alone or anything like that. It was just like one day I woke up and wanted to be dead. I honestly don’t know what to do