I feel so bad for my daughter

My daughter is really sad. Her and her cousin used to be so close. They have a 3 years age difference. They were best friends. My daughter is 12 and her cousin if 15 and would rather hang out with her teenage friends and boyfriend. She hasn't wanted to spend time with my daughter at all. We finally went over to my brothers house and my daughter was so excited. She told my niece about some dolls I got her for her birthday and she rolled her eyes and said "I stopped playing with dolls when I got boobs." My daughter looked sad and embarrassed and her cousin only stayed for an hour before leaving to go with her boyfriend. My daughter has been crying and sad that they aren't friends anymore...

Edit: All my brother said was "I see you've met Angsty Amy." He's been going through hell with her teens years and he's pretty much said he's just gonna pick his battles with her because he wants to strangle her half the time(not actual). I don't think talking to this Angsty teen will do any good because she's become a lot ruder than I remember.