Period is now 22 days late

My period was due to start on June 1st. I have yet to start. I am always very regular. Every 28 days. I have been late twice in my life (my pregnancy with my daughter and my miscarriage). I have a lot of pregnancy symptoms, but I'm just worried that it's all in my head. My breasts are sore, back aches, extremely tired, emotional, and I started to have breakouts on my face (I've never had acne issues). I have taken pregnancy tests and they are all negative. I go to the doctor next Tuesday to get blood work. Has this happened to anyone and they turned out to be pregnant?