Gripe Water

My LO is 4 weeks old and seems to have the most gas/fussiness in the evening between 10pm-12am (Lots of screaming and hard console shortly after eating). After lots of rocking and massaging she will eventually settle down by being breastfed for a few minutes (she typically gets a bottle around 10pm so I don't think it's hunger). I would like to try giving her gripe water but I am not sure when/how (I.e. Before or after a bottle, in the bottle, etc). Also trying to figure out if it is colic, gas, normal etc! 

The instructions are not specific as to when to administer it, just the recommended dosage. I bought the Little Remedies brand. 

What have you tried and has it worked?