Has anyone needed to take a 2nd round of misoprostol to pass the miscarriage? I took 2 doses 24 hours apart last week and went for my ultrasound today to make sure everything had passed and there was still some placental tissue up top of my uterus so doctor gave me a second round of misoprostol to take to pass it. It was aweful for me the first time and I'm scared it is going to be the same this time. Has anyone else needed two separate rounds of misoprostol a week apart to pass everything? Did it work? I'm very nervous I will need a D&C and I really don't want one.