My mother is just.....ugh!!!!!! HELP!

So here is a little back info, I have no relationship with my mothers extended family because they have never shown an interest in my life, I mean I even got married and no one from her side of the family even sent a text saying congratulations. My mother goes out to see them for a month or two out of the year, but I have no relationship with any of them. In fact my mother recently broke her back and I had to have my wife fly out there to get her because none of her family wanted to help out (my mother lives with my wife and myself due to her health issues)

So today my mother says to me “oh yeah so it’s so great you know your cousin is pregnant and due in September” and I’m looking at her like 1- I don’t give a shit about these people and 2- we have been trying to get pregnant for over a year, why are you even bringing this up. She starts crying and getting hysterical when I told her as usual that I don’t care and please don’t involve me in any of that, and now she is continually being passive aggressive and making slick comments about us trying to get pregnant, and we shouldn’t because I suffer from depression and it’s not fair to the baby, mind you my father suffered from paranoid schizophrenia.

I know she is my mother, we have a complicated relationship, my father died 8 years ago and my sister the following year from a drug overdose. So I’m trying to tread lightly because I am her only daughter but I am truly starting to feel like a punching bag. She has been back a month and has known about my cousin since before she got back, so I feel like she is just digging at me.

So here is my question, should I care? Should I be upset? I am just so upset at her I feel numb, and just wanting some advice outside my wife and friends because they can get territorial and just agree with me to support me.

So, how would you handle this?