Polyps and hyperplasia

Jamie

We spent all of 2023 doing IVF. Retrieval went well, got 2 euploid embryos, good grading. Prior to 1st transfer a SIS revealed multiple polyps, I had a hysteroscopy Polypectomy & d&c, 2 months later we transferred our 5AA euploid embryo and it failed. 2nd transfer of our last embryo 6AB also failed. Now I had a pap in Dec 2023 was abnormal and never had abnormal prior. Did further biopsies and showed atypical hyperplasia of the endometrium. I am seeing a gyn oncologist and just had a hysteroscopy S&s and iud placement to see if it regresses. I have to wait 9-12 months to try again for fertility as long as I’m in the clear, otherwise hysterectomy is in order sooner than later, and ultimately I will have a hysterectomy as it is definitive treatment. My major dilemma is that I’m 40.4. I’ve never had a child. I’m so torn as now I’ll have to wait a year and then be a year older, and what if IVF doesn’t work again and then I’m back to square one and have more endometrial issues. It’s such a hard decision. Has anyone had this happen? I’m concerned the stims will make everything worse. I can’t have estrogen anymore as the atypical hyperplasia is estrogen driven. My oncologist seems hopeful with the iud for now it will regress for me to try for IVF again, but I have such a hard time deciding if enough is enough and give up my dream to be a mom and not knowing if things could become worse if I do try.

Thanks for reading my long post.

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