Does Benadry have the opposites effect on a pregnant person? I couldn't breathe so I got up to take one and now I'm wide awake!! I don't remember it having this effect on me with my first one, and that was only 2-3 years ago .. Ugh. 10 weeks and I can't sleep! During the day I can barely keep my eyes open because I'm so tired and now 330am I'm wide awake .. My husband is gonna think I'm nuts if he wakes up and sees me sitting up awake on our couch in the dark lol