Help with weight

Ok so I am 220 5'3. I don't not feel comfortable with my body I need to lose some weight. But I have thyroid problems and a disability with my feet so I can't run or walk to much and I have pcos and its all really hard to lose weight when pcos is weight gain and my thyroid its sooo hard to lose weight or I lose it and it comes back twice as much any help ? Of some stuff to do