IUI question?

Mrs❤️
I have my 4th <a href="https://glowing.com/glow-fertility-program">IUI</a> tomorrow morning, the last one I had hurt pretty bad and I cramped for several days after.. I'm wondering if there's anything I can take an hour before to help relax my vaginal walls/utuerus? Tylenol maybe? I heard ibuprofen hurts your chances of conception? Any advice??