Should I take my 3 month old on a 4 hour flight?

I would like to hear opinions from parents who've flown with infants before. I'm going to ask her paediatrician. I have a baby due end of June and my sisters wedding is in October. I'm thinking of just staying home because I'm scared to put my little baby's body through all the stress of flying. I've heard there ears pop which is painful for them and they scream the whole time sometimes. Do they go through a jet leg and need to recover? What are your experiences? Also any tips on making flying with an infant easier and less stressful? 

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