Help! I've posted before and only got one response

My LO is refusing to take a bottle. I have tried 5 different kinds of bottles all with different flows. We have tried each one with breast milk and Formula. Different people in the family have even tried to feed him, but he's not having it. My SO used to give him a bottle before bed every night since birth, then one night my LO just started to refuse it. He will scream and throw a fit until he gets the breast. There was one night I had left for an hour and my LO wouldnt take the bottle so he cried himself to sleep. I'm trying to go back to work but wont be able to until he starts taking the bottle. He'll be 3 months on the 28th. Please help