Anyone else had their relationship destroyed by thyroid cancer?

My husband has always been jokingly snarky, but not cruel. Three years ago, he discovered he had thyroid cancer and had to have his thyroid removed.

Ever since, he has had INTENSE mood swings and when he's mean, he's very mean. (Threatens to leave me and take our daughter away from me because I ask him to throw his trash in the bin instead of dropping it to the floor where he stands, for example). He doesn't seem to care anymore about how he affects others, and he used to. He takes meds but I don't think the dosage is right. I've tried to talk to him about it when we're both calm, but he says he feels normal so therefore it's me who has changed. He refuses to mention it to his doctor because he thinks he's acting as he always has. It's even gotten to the point where he told me his cancer was my fault because I encouraged him to get the lump in his throat checked out, and if I hadn't, he would have lived blissfully unaware and he'd still have his thyroid. (His cancer was a very slow growing type so he says it would have never bothered him).

I don't blame him, obviously. He had a gland that largely affects mood removed from his body. But it's so, so frustrating. The mood swings are getting so hard to navigate. I'm constantly walking on eggshells, but it's also as if the room I'm walking through is on fire. It's hard constantly being labeled his enemy when I've been his teammate for the last decade.

Anyone else have experiences like this?