Estradiol side effects?

Hello, I had a question and wondering if anyone can relate. I am on Prometrium vaginal suppositories along with progesterone in oil. I also take Estradiol tabs 4x daily orally.

I had my second beta last Tuesday when I was 14dp5dt and my estrogen was low so they increased my estradiol by adding in 3x daily vaginally. So today I’m 5w3d. I feel like the last couple of days I’ve noticed a slight itch. It’s not horrible at all or nothing I can’t handle, just enough to notice and I can only suspect it’s the Estradiol because Ive been on Prometrium before and it’s never bothered me. Also, the pills are blue so of course that’s what comes out 🙄 lovely. I’m not highly concerned but wanted to see if this was common as I’ve not seen too many people talk about taking estradiol vaginally. I’m not too sensitive down there, as in I’m not sensitive to soaps, I never get yeast infections or BV or anything like that so I’m not too worried but didn’t know if this is something I should call the nurse about. Thanks!