How do you know when it's time to end a friendship?

I've known this woman since first grade, we've been best friends ever since, but for the last 5ish years it's been solely about her. For example, she made me cry on my wedding day (not in a good way). Several other incidents like this. And it's not jealousy, she got married right after me a month later, but it's like if the attention isn't always on her, then she has an issue.

I literally told her my uncle died via text and she kept talking about her issues. Never acknowledged it. What the fuck? To this day, I still think she doesn't know.

And did she check on me post partum? Well I think you know the answer to that question based on what I've written 🥺

I've known her 23 years. What are your suggestions? It's impossible to talk to her. How would you handle the situation?

Thanks!

PS I didn't know where to post this lol.