I'm 26 and I've never had an orgasm

Ami • Registered Nurse. Femme Lesbian. Intersectional Feminist. Vegetarian. Leo.
I'm 26 years old and I've never been able to have an orgasm. Not with partners but also not by myself when masturbating. I do have a fairly high sex drive, and I almost always want to masturbate or have sex with someone, so a lack of desire isn't the problem. But I'm starting to wonder if it's just impossible for some women to be able to reach orgasm?
I have slept with a few dozen people (I sleep with women) in my life so far. Most of them were great in bed, and not selfish, and really dedicated to helping me try and have an orgasm. But it never happened, not even when I was in long term relationships where we had time to really get to know each other's bodies. I've explored lots of different things sexually with the girlfriends I've had, but still with no results. 
On my own, I've also tried everything I can think of. Lubes, vibrators, shower head, bathtub faucet, watching porn, reading erotic literature, fantasizing, etc. I've tried going hard and fast and slow and gentle and everything in between. I've even tried substances to help me relax and get out of my head and into my body, in case that was the problem. With masturbating I've tried alcohol, weed, benzodiazepines, even MDMA. But. Still. No. Orgasms. 
Does anyone have any reputable information about whether or not it's possible that some women are just anorgasmic for their entire life? Is there even any hope for me?